Hybrid Quinoline-Thiosemicarbazone Therapeutics as a New Treatment Opportunity for Alzheimer’s Disease‒Synthesis, In Vitro Cholinesterase Inhibitory Potential and Computational Modeling Analysis

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the leading cause of dementia worldwide. The limited pharmacological approaches based on cholinesterase inhibitors only provide symptomatic relief to AD patients. Moreover, the adverse side effects such as nausea, vomiting, los...

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Detalhes bibliográficos

Principais autores:	Sumera Zaib, Rubina Munir, Muhammad Tayyab Younas, Naghmana Kausar, Aliya Ibrar, Sehar Aqsa, Noorma Shahid, Tahira Tasneem Asif, Hashem O. Alsaab, Imtiaz Khan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-10-01
coleção:	Molecules
Assuntos:	quinoline thiosemicarbazone molecular design hybridization Alzheimer’s disease neurodegeneration
Acesso em linha:	https://www.mdpi.com/1420-3049/26/21/6573
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