Entorhinal cortex atrophy mediates the association of plasma p-tau181, GFAP, and NfL with cognitive impairment in Parkinson’s disease

BackgroundCognitive impairment is a major determinant of disability in Parkinson’s disease (PD), underscoring the need for biomarkers that reflect its underlying pathophysiology. Plasma biomarkers, including phosphorylated tau at threonine 181 (p-tau181), glial fibrillary acidic protein (GFAP), and...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Qiangqiang Wan, Xinyu Dai, Zhongwen Zhang, Ping Shan, Gui Mei, Luqi Huang, Lan Wang, Hongfen Peng
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-05-01
Colecção:	Frontiers in Aging Neuroscience
Assuntos:	cognitive impairment entorhinal cortex neurofilament light chain Parkinson’s disease plasma biomarkers
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fnagi.2026.1791756/full
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!