Entorhinal cortex atrophy mediates the association of plasma p-tau181, GFAP, and NfL with cognitive impairment in Parkinson’s disease

BackgroundCognitive impairment is a major determinant of disability in Parkinson’s disease (PD), underscoring the need for biomarkers that reflect its underlying pathophysiology. Plasma biomarkers, including phosphorylated tau at threonine 181 (p-tau181), glial fibrillary acidic protein (GFAP), and...

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Bibliografske podrobnosti

Principais autores:	Qiangqiang Wan, Xinyu Dai, Zhongwen Zhang, Ping Shan, Gui Mei, Luqi Huang, Lan Wang, Hongfen Peng
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2026-05-01
Serija:	Frontiers in Aging Neuroscience
Teme:	cognitive impairment entorhinal cortex neurofilament light chain Parkinson’s disease plasma biomarkers
Online dostop:	https://www.frontiersin.org/articles/10.3389/fnagi.2026.1791756/full
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