Mitochondrial Uncoupler, 2,4-Dinitrophenol, Reduces Spinal Cord Paralysis and Retinal Ganglion Cell Loss in the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis

Optic neuritis is an inflammatory demyelinating disease of the optic nerve that often occurs in multiple sclerosis (MS) patients. Sixty percent of patients develop some level of permanent visual loss due to retinal ganglion cell (RGC) damage following optic neuritis, with no known treatment to preve...

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Hlavní autoři:	Nuala O’Neill, Reas S. Khan, Suad Abd Alhadi, Kimberly E. Dine, John G. Geisler, Brahim Chaqour, Ahmara G. Ross, Kenneth S. Shindler
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2025-01-01
Edice:	Biomolecules
Témata:	EAE optic neuritis RGC neuroprotection dinitrophenol mitochondrial uncoupling agent
On-line přístup:	https://www.mdpi.com/2218-273X/15/2/189
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