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Extracellular vesicles from mesenchymal stem cells improve neuroinflammation and neurotransmission in hippocampus and cognitive impairment in rats with mild liver damage and minimal hepatic encephalopathy

Abstract Background Patients with steatotic liver disease may show mild cognitive impairment. Rats with mild liver damage reproduce this cognitive impairment, which is mediated by neuroinflammation that alters glutamate neurotransmission in the hippocampus. Treatment with extracellular vesicles (EV)...

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主要な著者: Gergana Mincheva, Victoria Moreno-Manzano, Vicente Felipo, Marta Llansola
フォーマット: Artigo
言語:Inglês
出版事項: BMC 2024-12-01
シリーズ:Stem Cell Research & Therapy
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オンライン・アクセス:https://doi.org/10.1186/s13287-024-04076-6
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