SP1-induced upregulation of lncRNA SPRY4-IT1 exerts oncogenic properties by scaffolding EZH2/LSD1/DNMT1 and sponging miR-101-3p in cholangiocarcinoma

Abstract Background Accumulating evidence has indicated that long non-coding RNAs (lncRNAs) behave as a novel class of transcription products during multiple cancer processes. However, the mechanisms responsible for their alteration in cholangiocarcinoma (CCA) are not fully understood. Methods The e...

Descrición completa

Detalles Bibliográficos

Principais autores:	Yi Xu, Yue Yao, Xingming Jiang, Xiangyu Zhong, Zhidong Wang, Chunlong Li, Pengcheng Kang, Kaiming Leng, Daolin Ji, Zhenglong Li, Lining Huang, Wei Qin, Yunfu Cui
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2018-04-01
Series:	Journal of Experimental & Clinical Cancer Research
Assuntos:	Cholangiocarcinoma lncRNA SPRY4-IT1 Scaffold Oncogenic properties
Acceso en liña:	http://link.springer.com/article/10.1186/s13046-018-0747-x
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!