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Plasma therapy leads to an increase in functional IgA and IgM concentration in the blood and saliva of a patient with X-linked agammaglobulinemia

Abstract Background Patients with X-linked agammaglobulinemia (XLA) are protected against invasive bacterial infections due to IgG replacement therapy, but are still at higher risk for mucosal infections of the gut and respiratory tract. This might be explained by to the lack of IgA and IgM, as thes...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Jeroen D. Langereis, Joannes F. M. Jacobs, Marien I. de Jonge, Marcel van Deuren
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2019-05-01
Schriftenreihe:Journal of Translational Medicine
Schlagworte:
Agammaglobulinemia
Haemophilus influenzae
IgA
IgM
Agglutination
Complement
Online-Zugang:http://link.springer.com/article/10.1186/s12967-019-1928-x
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