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Plasma therapy leads to an increase in functional IgA and IgM concentration in the blood and saliva of a patient with X-linked agammaglobulinemia

Abstract Background Patients with X-linked agammaglobulinemia (XLA) are protected against invasive bacterial infections due to IgG replacement therapy, but are still at higher risk for mucosal infections of the gut and respiratory tract. This might be explained by to the lack of IgA and IgM, as thes...

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Principais autores: Jeroen D. Langereis, Joannes F. M. Jacobs, Marien I. de Jonge, Marcel van Deuren
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-05-01
coleção:Journal of Translational Medicine
Assuntos:
Agammaglobulinemia
Haemophilus influenzae
IgA
IgM
Agglutination
Complement
Acesso em linha:http://link.springer.com/article/10.1186/s12967-019-1928-x
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