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The mechanism and therapeutic prospect of HIF-1 α/BNIP3 pathway in regulating mitophagy in tubulointerstitial fibrosis

Tubulointerstitial fibrosis (TIF) is a key pathological hallmark and a major determinant of end-stage renal disease (ESRD). The mechanisms of TIF remain unclear, and there are currently no specific drugs to slow or reverse its progression. Notably, due to the kidney’s unique structure, the course of...

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Autors principals: Xinru Wang, Zhaoan Guo
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis Group 2026-12-01
Col·lecció:Renal Failure
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Accés en línia:https://www.tandfonline.com/doi/10.1080/0886022X.2026.2667684
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