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The mechanism and therapeutic prospect of HIF-1 α/BNIP3 pathway in regulating mitophagy in tubulointerstitial fibrosis

Tubulointerstitial fibrosis (TIF) is a key pathological hallmark and a major determinant of end-stage renal disease (ESRD). The mechanisms of TIF remain unclear, and there are currently no specific drugs to slow or reverse its progression. Notably, due to the kidney’s unique structure, the course of...

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Bibliografiska uppgifter
Huvudupphov: Xinru Wang, Zhaoan Guo
Materialtyp: Artigo
Språk:Inglês
Utgiven: Taylor & Francis Group 2026-12-01
Serie:Renal Failure
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Länkar:https://www.tandfonline.com/doi/10.1080/0886022X.2026.2667684
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