Ageing-associated long non-coding RNA extends lifespan and reduces translation in non-dividing cells
Abstract Genomes produce widespread long non-coding RNAs (lncRNAs) of largely unknown functions. We characterize aal1 (ageing-associated lncRNA), which is induced in quiescent fission yeast cells. Deletion of aal1 shortens the chronological lifespan of non-dividing cells, while ectopic overexpressio...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Springer Nature
2024-10-01
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| Seria: | EMBO Reports |
| Hasła przedmiotowe: | |
| Dostęp online: | https://doi.org/10.1038/s44319-024-00265-9 |
| Etykiety: |
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