Combination Regimens of Favipiravir Plus Interferon Alpha Inhibit Chikungunya Virus Replication in Clinically Relevant Human Cell Lines

Chikungunya virus (CHIKV) is an alphavirus associated with a broad tissue tropism for which no antivirals or vaccines are approved. This study evaluated the antiviral potential of favipiravir (FAV), interferon-alpha (IFN), and ribavirin (RBV) against CHIKV as mono- and combination-therapy in cell li...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Evelyn J. Franco, Xun Tao, Kaley C. Hanrahan, Jieqiang Zhou, Jürgen B. Bulitta, Ashley N. Brown
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2021-02-01
Schriftenreihe:	Microorganisms
Schlagworte:	chikungunya virus favipiravir interferon-alpha combination therapy mathematical modeling
Online-Zugang:	https://www.mdpi.com/2076-2607/9/2/307
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