Alpha-synuclein activates the classical complement pathway and mediates complement-dependent cell toxicity
Abstract Background Synucleinopathies are characterized by neurodegeneration and deposition of the presynaptic protein α-synuclein in pathological protein inclusions. Growing evidence suggests the complement system not only has physiological functions in the central nervous system, but also is invol...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BMC
2021-08-01
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| シリーズ: | Journal of Neuroinflammation |
| 主題: | |
| オンライン･アクセス: | https://doi.org/10.1186/s12974-021-02225-9 |
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