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Higher-molecular-weight a-synuclein oligomers are increased in the brain cytosol of patients with dementia with Lewy bodies

Abstract The demonstration of MJFR14-6-4-2 proximity ligation assay positive aggregates in brains affected by Parkinson’s disease and LRRK2 mutations, motivated the analysis of α-synuclein oligomers in brain cytosol from dementia with Lewy bodies (DLB) and control cases by combining size-exclusion c...

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Hlavní autoři: Emil Gregersen, Mia R. Antorini, Lasse Reimer, Ludovica Zaccagnini, Dennis Selkoe, Tim Bartels, Poul Henning Jensen
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2026-02-01
Edice:npj Parkinson's Disease
On-line přístup:https://doi.org/10.1038/s41531-026-01301-2
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