Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78.

The 70-kDa heat shock proteins (Hsp70) are chaperones with central roles in processes that involve polypeptide remodeling events. Hsp70 proteins consist of two major functional domains: an N-terminal nucleotide binding domain (NBD) with ATPase activity, and a C-terminal substrate binding domain (SBD...

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Библиографические подробности

Главные авторы:	Magdalena Wisniewska, Tobias Karlberg, Lari Lehtiö, Ida Johansson, Tetyana Kotenyova, Martin Moche, Herwig Schüler
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Public Library of Science (PLoS) 2010-01-01
Серии:	PLoS ONE
Online-ссылка:	http://europepmc.org/articles/PMC2803158?pdf=render
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