ARHGAP6 Suppresses Breast Cancer Tumor Growth by Promoting Ferroptosis via RhoA-ROCK1-p38 MAPK Signaling

Background: Ferroptosis, a distinct iron-dependent form of regulated cell death, is induced by severe lipid peroxidation due to reactive oxygen species (ROS) generation. Breast cancer patient survival is correlated with the tumor-suppressing properties of Rho guanosine triphosphatase hydrolase enzym...

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Principais autores:	Xiaoqing Chen, Jing Zhu, Xiangzhi Li, Jintao Chen, Zhisheng Zhou, Xulong Fan, Ruijian Liang, Haiyan Liu, Dajiang Zhu
格式:	Artigo
語言:	Inglês
出版:	IMR Press 2024-01-01
叢編:	Frontiers in Bioscience-Landmark
主題:	breast cancer arhgap6 ferroptosis p38 mapk
在線閱讀:	https://www.imrpress.com/journal/FBL/29/1/10.31083/j.fbl2901006
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