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ARHGAP6 Suppresses Breast Cancer Tumor Growth by Promoting Ferroptosis via RhoA-ROCK1-p38 MAPK Signaling

Background: Ferroptosis, a distinct iron-dependent form of regulated cell death, is induced by severe lipid peroxidation due to reactive oxygen species (ROS) generation. Breast cancer patient survival is correlated with the tumor-suppressing properties of Rho guanosine triphosphatase hydrolase enzym...

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Bibliografiske detaljer
Principais autores: Xiaoqing Chen, Jing Zhu, Xiangzhi Li, Jintao Chen, Zhisheng Zhou, Xulong Fan, Ruijian Liang, Haiyan Liu, Dajiang Zhu
Format: Artigo
Sprog:Inglês
Udgivet: IMR Press 2024-01-01
Serier:Frontiers in Bioscience-Landmark
Fag:
Online adgang:https://www.imrpress.com/journal/FBL/29/1/10.31083/j.fbl2901006
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