ARHGAP6 Suppresses Breast Cancer Tumor Growth by Promoting Ferroptosis via RhoA-ROCK1-p38 MAPK Signaling
Background: Ferroptosis, a distinct iron-dependent form of regulated cell death, is induced by severe lipid peroxidation due to reactive oxygen species (ROS) generation. Breast cancer patient survival is correlated with the tumor-suppressing properties of Rho guanosine triphosphatase hydrolase enzym...
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| Principais autores: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
IMR Press
2024-01-01
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| Serier: | Frontiers in Bioscience-Landmark |
| Fag: | |
| Online adgang: | https://www.imrpress.com/journal/FBL/29/1/10.31083/j.fbl2901006 |
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