Iron metabolism mediates microglia susceptibility in ferroptosis

Ferroptosis is implicated in a range of brain disorders, but it is unknown whether neurons or glia in the brain are particularly effected. Here, we report that primary cortical astrocytes (PA), microglia (PM), and neurons (PN) varied in their sensitivities to ferroptosis. Specifically, PM were the m...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Lingling Jiao, Xiaolan Li, Yuxiang Luo, Junfen Wei, Xulong Ding, Huan Xiong, Xuesong Liu, Peng Lei
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2022-08-01
Цуврал:	Frontiers in Cellular Neuroscience
Нөхцлүүд:	cell death ferroptosis iron metabolism glia neurons
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fncel.2022.995084/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!