Iron metabolism mediates microglia susceptibility in ferroptosis

Ferroptosis is implicated in a range of brain disorders, but it is unknown whether neurons or glia in the brain are particularly effected. Here, we report that primary cortical astrocytes (PA), microglia (PM), and neurons (PN) varied in their sensitivities to ferroptosis. Specifically, PM were the m...

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Bibliographic Details

Main Authors:	Lingling Jiao, Xiaolan Li, Yuxiang Luo, Junfen Wei, Xulong Ding, Huan Xiong, Xuesong Liu, Peng Lei
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2022-08-01
Series:	Frontiers in Cellular Neuroscience
Subjects:	cell death ferroptosis iron metabolism glia neurons
Online Access:	https://www.frontiersin.org/articles/10.3389/fncel.2022.995084/full
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