Iron metabolism mediates microglia susceptibility in ferroptosis

Ferroptosis is implicated in a range of brain disorders, but it is unknown whether neurons or glia in the brain are particularly effected. Here, we report that primary cortical astrocytes (PA), microglia (PM), and neurons (PN) varied in their sensitivities to ferroptosis. Specifically, PM were the m...

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Hlavní autoři:	Lingling Jiao, Xiaolan Li, Yuxiang Luo, Junfen Wei, Xulong Ding, Huan Xiong, Xuesong Liu, Peng Lei
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2022-08-01
Edice:	Frontiers in Cellular Neuroscience
Témata:	cell death ferroptosis iron metabolism glia neurons
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fncel.2022.995084/full
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