Proteo-Genomic Analysis Identifies Two Major Sites of Vulnerability on Ebolavirus Glycoprotein for Neutralizing Antibodies in Convalescent Human Plasma

Three clinically relevant ebolaviruses – Ebola (EBOV), Bundibugyo (BDBV), and Sudan (SUDV) viruses, are responsible for severe disease and occasional deadly outbreaks in Africa. The largest Ebola virus disease (EVD) epidemic to date in 2013-2016 in West Africa highlighted the urgent need for counter...

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Bibliografski detalji

Glavni autori:	Pavlo Gilchuk, Adrian Guthals, Stefano R. Bonissone, Jared B. Shaw, Philipp A. Ilinykh, Kai Huang, Robin G. Bombardi, Jenny Liang, Ariadna Grinyo, Edgar Davidson, Elaine C. Chen, Bronwyn M. Gunn, Galit Alter, Erica Ollmann Saphire, Benjamin J. Doranz, Alexander Bukreyev, Larry Zeitlin, Natalie Castellana, James E. Crowe
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2021-07-01
Serija:	Frontiers in Immunology
Teme:	ebolavirus ebolavirus infection glycoprotein proteo-genomics convalescent plasma viral antibodies
Online pristup:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.706757/full
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