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Convergence of a common solution for broad ebolavirus neutralization by glycan cap-directed human antibodies

Summary: Antibodies that target the glycan cap epitope on the ebolavirus glycoprotein (GP) are common in the adaptive response of survivors. A subset is known to be broadly neutralizing, but the details of their epitopes and basis for neutralization are not well understood. Here, we present cryoelec...

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Principais autores: Charles D. Murin, Pavlo Gilchuk, Philipp A. Ilinykh, Kai Huang, Natalia Kuzmina, Xiaoli Shen, Jessica F. Bruhn, Aubrey L. Bryan, Edgar Davidson, Benjamin J. Doranz, Lauren E. Williamson, Jeffrey Copps, Tanwee Alkutkar, Andrew I. Flyak, Alexander Bukreyev, James E. Crowe, Jr., Andrew B. Ward
格式: Artigo
語言:Inglês
出版: Elsevier 2021-04-01
叢編:Cell Reports
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在線閱讀:http://www.sciencedirect.com/science/article/pii/S2211124721002989
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