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Association of interacting genes in the toll-like receptor signaling pathway and the antibody response to pertussis vaccination.

BACKGROUND: Activation of the Toll-like receptor (TLR) signaling pathway through TLR4 may be important in the induction of protective immunity against Bordetella pertussis with TLR4-mediated activation of dendritic and B cells, induction of cytokine expression, and reversal of tolerance as crucial s...

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Principais autores: Tjeerd G Kimman, Sander Banus, Naomi Reijmerink, Johan Reimerink, Foekje F Stelma, Gerard H Koppelman, Carel Thijs, Dirkje S Postma, Marjan Kerkhof
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2008-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC2573957?pdf=render
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