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Mechanism of ribosome rescue by alternative ribosome-rescue factor B

Rescue of ribosomes stalled on non-stop mRNA is essential for cell viability, and several rescue systems to resolve stalling exist in bacteria. Here, the authors use rapid kinetics and cryo-EM to reveal the pathway and selectivity mechanism of ArfB-mediated ribosome rescue.

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Bibliografiske detaljer
Principais autores: Kai-Hsin Chan, Valentyn Petrychenko, Claudia Mueller, Cristina Maracci, Wolf Holtkamp, Daniel N. Wilson, Niels Fischer, Marina V. Rodnina
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2020-08-01
Serier:Nature Communications
Online adgang:https://doi.org/10.1038/s41467-020-17853-7
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