Bortezomib-based antibody depletion for refractory autoimmune hematological diseases
Abstract: Certain patients with antibody-mediated autoimmune disease exhibit poor responses to conventional immunosuppression, including B-cell depletion with rituximab. Proteasome inhibitors such as bortezomib demonstrate pleiotropic immunomodulatory effects, including direct toxicity to antibody-p...
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| Autori principali: | , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2016-11-01
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| Serie: | Blood Advances |
| Accesso online: | http://www.sciencedirect.com/science/article/pii/S2473952920303670 |
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