Sustained treatment of retinal vascular diseases with self-aggregating sunitinib microparticles

Neovascular age-related macular degeneration and diabetic retinopathy are currently treated with repeated intravitreous injections of VEGF neutralizing proteins. Here the authors develop a microparticle-loaded tyrosine kinase inhibitor therapy, which is effective for six months after a single inject...

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מידע ביבליוגרפי

Principais autores:	Hiroki Tsujinaka, Jie Fu, Jikui Shen, Yun Yu, Zibran Hafiz, Joshua Kays, David McKenzie, Delia Cardona, David Culp, Ward Peterson, Brian C. Gilger, Christopher S. Crean, Jin-Zhong Zhang, Yogita Kanan, Weiling Yu, Jeffrey L. Cleland, Ming Yang, Justin Hanes, Peter A. Campochiaro
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Nature Portfolio 2020-02-01
סדרה:	Nature Communications
גישה מקוונת:	https://doi.org/10.1038/s41467-020-14340-x
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