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A link between the fibroblast growth factor axis and the miR‐16 family reveals potential new treatment combinations in mesothelioma

Malignant pleural mesothelioma (MPM) is an aggressive malignancy with very limited therapeutic options. Fibroblast growth factor (FGF) signals play important roles in mesothelioma cell growth. Several FGFs and FGF receptors (FGFRs) are predicted targets of the miR‐15/16 family, which is downregulate...

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Bibliographic Details
Main Authors: Karin Schelch, Michaela B. Kirschner, Marissa Williams, Yuen Y. Cheng, Nico vanZandwijk, Michael Grusch, Glen Reid
Format: Artigo
Language:Inglês
Published: Wiley 2018-01-01
Series:Molecular Oncology
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Online Access:https://doi.org/10.1002/1878-0261.12150
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