Inactivation influences the extent of inhibition of voltage-gated Ca+2 channels by Gem—implications for channelopathies

Voltage-gated Ca2+ channels (VGCC) directly control muscle contraction and neurotransmitter release, and slower processes such as cell differentiation, migration, and death. They are potently inhibited by RGK GTP-ases (Rem, Rem2, Rad, and Gem/Kir), which decrease Ca2+ channel membrane expression, as...

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Bibliografske podrobnosti

Principais autores:	Salma Allam, Rose Levenson-Palmer, Zuleen Chia Chang, Sukhjinder Kaur, Bryan Cernuda, Ananya Raman, Audrey Booth, Scott Dobbins, Gabrielle Suppa, Jian Yang, Zafir Buraei
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2023-08-01
Serija:	Frontiers in Physiology
Teme:	ataxia Ca2+ channelopathy GTPase heart ion channel
Online dostop:	https://www.frontiersin.org/articles/10.3389/fphys.2023.1155976/full
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