Abrogation of plasminogen activator inhibitor-1-vitronectin interaction ameliorates acute kidney injury in murine endotoxemia.

Sepsis-induced acute kidney injury (AKI) contributes to the high mortality and morbidity in patients. Although the pathogenesis of AKI during sepsis is poorly understood, it is well accepted that plasminogen activator inhibitor-1 (PAI-1) and vitronectin (Vn) are involved in AKI. However, the functio...

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Bibliografski detalji

Glavni autori:	Kamlesh K Gupta, Deborah L Donahue, Mayra J Sandoval-Cooper, Francis J Castellino, Victoria A Ploplis
Format:	Artigo
Jezik:	Inglês
Izdano:	Public Library of Science (PLoS) 2015-01-01
Serija:	PLoS ONE
Online pristup:	http://europepmc.org/articles/PMC4370643?pdf=render
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