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Super-enhancer acquisition drives oncogene expression in triple negative breast cancer.

Triple Negative Breast Cancer (TNBC) is a heterogeneous disease lacking known molecular drivers and effective targeted therapies. Cytotoxic chemotherapy remains the mainstay of treatment for TNBCs, which have significantly poorer survival rates compared to other breast cancer subtypes. In addition t...

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Detalhes bibliográficos
Principais autores: Ryan Raisner, Russell Bainer, Peter M Haverty, Kelli L Benedetti, Karen E Gascoigne
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2020-01-01
coleção:PLoS ONE
Acesso em linha:https://doi.org/10.1371/journal.pone.0235343
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