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Super-enhancer acquisition drives oncogene expression in triple negative breast cancer.

Triple Negative Breast Cancer (TNBC) is a heterogeneous disease lacking known molecular drivers and effective targeted therapies. Cytotoxic chemotherapy remains the mainstay of treatment for TNBCs, which have significantly poorer survival rates compared to other breast cancer subtypes. In addition t...

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Hlavní autoři: Ryan Raisner, Russell Bainer, Peter M Haverty, Kelli L Benedetti, Karen E Gascoigne
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2020-01-01
Edice:PLoS ONE
On-line přístup:https://doi.org/10.1371/journal.pone.0235343
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