Parent-of-origin-specific DNA replication timing is confined to large imprinted regions

Summary: Genomic imprinting involves differential DNA methylation and gene expression between homologous paternal and maternal loci. It remains unclear, however, whether DNA replication also shows parent-of-origin-specific patterns at imprinted or other genomic regions. Here, we investigate genome-w...

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Detalhes bibliográficos

Principais autores:	Matthew M. Edwards, Ning Wang, Ido Sagi, Shay Kinreich, Nissim Benvenisty, Jeannine Gerhardt, Dieter Egli, Amnon Koren
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-09-01
coleção:	Cell Reports
Assuntos:	CP: Molecular biology CP: Genomics
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211124724010519
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