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Insulin Regulates the Activity of the High-Affinity Choline Transporter CHT.

Studies in humans and animal models show that neuronal insulin resistance increases the risk of developing Alzheimer's Disease (AD), and that insulin treatment may promote memory function. Cholinergic neurons play a critical role in cognitive and attentional processing and their dysfunction early in...

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Autori principali: Katherine J Fishwick, R Jane Rylett
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2015-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC4498808?pdf=render
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