Rutin Potentially Binds the Gamma Secretase Catalytic Site, Down Regulates the Notch Signaling Pathway and Reduces Sphere Formation in Colonospheres

Rutin, a natural flavonol, can modulate molecular signaling pathways and has considerable potential in cancer treatment. However, little is known about the effect of rutin on the notch signaling pathway (NSP) in cancer and cancer stem-like cells. In this study, we explored the effect of rutin on gam...

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Prif Awduron:	Atul Kumar Singh, Mohd Shuaib, Kumari Sunita Prajapati, Shashank Kumar
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	MDPI AG 2022-09-01
Cyfres:	Metabolites
Pynciau:	gamma secretase notch signaling pathway flavonoid colon cancer stem-like cells
Mynediad Ar-lein:	https://www.mdpi.com/2218-1989/12/10/926
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!