Rutin Potentially Binds the Gamma Secretase Catalytic Site, Down Regulates the Notch Signaling Pathway and Reduces Sphere Formation in Colonospheres

Rutin, a natural flavonol, can modulate molecular signaling pathways and has considerable potential in cancer treatment. However, little is known about the effect of rutin on the notch signaling pathway (NSP) in cancer and cancer stem-like cells. In this study, we explored the effect of rutin on gam...

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Autors principals:	Atul Kumar Singh, Mohd Shuaib, Kumari Sunita Prajapati, Shashank Kumar
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2022-09-01
Col·lecció:	Metabolites
Matèries:	gamma secretase notch signaling pathway flavonoid colon cancer stem-like cells
Accés en línia:	https://www.mdpi.com/2218-1989/12/10/926
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