Impact of APOE ε4 Carrier Status on Associations Between Subthreshold, Positive Amyloid-β Deposition, Brain Function, and Cognitive Performance in Cognitively Normal Older Adults: A Prospective Study

BackgroundA growing body of evidence suggests a deteriorating effect of subthreshold amyloid-beta (Aβ) accumulation on cognition before the onset of clinical symptoms of Alzheimer's disease (AD). Despite the association between the Aβ-dependent pathway and the APOE ε4 allele, the impact of this alle...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Dong Woo Kang, Sheng-Min Wang, Yoo Hyun Um, Nak-Young Kim, Chang Uk Lee, Hyun Kook Lim
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-05-01
Colecção:	Frontiers in Aging Neuroscience
Assuntos:	APOE ε4 allele subthreshold amyloid-beta regional homogeneity functional connectivity cognitively normal older adults
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fnagi.2022.871323/full
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!