Protein kinase C activation stabilizes LDL receptor mRNA via the JNK pathway in HepG2 cells*[S]

LDL is the most abundant cholesterol transport vehicle in plasma and a major prognostic indicator of atherosclerosis. Hepatic LDL receptors limit circulating LDL levels, since cholesterol internalized by the liver can be excreted. As such, mechanisms regulating LDL receptor expression in liver cells...

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Bibliografische gegevens

Hoofdauteurs:	Noelle B. Vargas, Brandy Y. Brewer, Terry B. Rogers, Gerald M. Wilson
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Elsevier 2009-03-01
Reeks:	Journal of Lipid Research
Onderwerpen:	signal transduction mitogen-activated protein kinase lipoprotein metabolism mRNA turnover gene expression
Online toegang:	http://www.sciencedirect.com/science/article/pii/S0022227520308828
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