Protein kinase C activation stabilizes LDL receptor mRNA via the JNK pathway in HepG2 cells*[S]

LDL is the most abundant cholesterol transport vehicle in plasma and a major prognostic indicator of atherosclerosis. Hepatic LDL receptors limit circulating LDL levels, since cholesterol internalized by the liver can be excreted. As such, mechanisms regulating LDL receptor expression in liver cells...

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Detalhes bibliográficos

Principais autores:	Noelle B. Vargas, Brandy Y. Brewer, Terry B. Rogers, Gerald M. Wilson
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2009-03-01
coleção:	Journal of Lipid Research
Assuntos:	signal transduction mitogen-activated protein kinase lipoprotein metabolism mRNA turnover gene expression
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0022227520308828
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