Natural antagonistic flavones for AhR inhibit indoxyl sulfate-induced inflammatory gene expression in vitro and renal pathological damages in vivo

Background: Uremic toxin indoxyl sulfate (IS) induces vascular inflammation, a crucial event in renal failure, and vascular complications in patients with chronic kidney disease (CKD). In endothelial cells, IS increases the production of inflammatory cytokines partially via the activation of the ary...

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Principais autores:	Tomomi Iwashima, Yui Takemura, Yoshimi Kishimoto, Chihiro Ono, Ayano Watanabe, Kaoruko Iida
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Swedish Nutrition Foundation 2024-07-01
Colecção:	Food & Nutrition Research
Assuntos:	aryl hydrocarbon receptor chrysin endothelium flavone indoxyl sulfate inflammation renal failure
Acesso em linha:	https://foodandnutritionresearch.net/index.php/fnr/article/view/10032/17426
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