Natural antagonistic flavones for AhR inhibit indoxyl sulfate-induced inflammatory gene expression in vitro and renal pathological damages in vivo

Background: Uremic toxin indoxyl sulfate (IS) induces vascular inflammation, a crucial event in renal failure, and vascular complications in patients with chronic kidney disease (CKD). In endothelial cells, IS increases the production of inflammatory cytokines partially via the activation of the ary...

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Egile Nagusiak:	Tomomi Iwashima, Yui Takemura, Yoshimi Kishimoto, Chihiro Ono, Ayano Watanabe, Kaoruko Iida
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Swedish Nutrition Foundation 2024-07-01
Saila:	Food & Nutrition Research
Gaiak:	aryl hydrocarbon receptor chrysin endothelium flavone indoxyl sulfate inflammation renal failure
Sarrera elektronikoa:	https://foodandnutritionresearch.net/index.php/fnr/article/view/10032/17426
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