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Microglia-Mediated Phagocytosis in Alzheimer’s Disease: Mechanisms, Heterogeneity, and Therapeutic Insights

Microglia are the resident immune cells of the CNS, maintaining brain homeostasis partially through phagocytosis. In Alzheimer’s disease (AD), microglial phagocytosis is significantly impaired, contributing to the accumulation of pathological aggregates. Microglial phenotypes are dynamic and can shi...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Halimatu Hassan, Charlotte Rawlinson, Yu-Long Lan, Stuart Jenkins, Ruoli Chen
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2025-11-01
Schriftenreihe:Biomolecules
Schlagworte:
Alzheimer’s disease
microglia
phagocytosis
neuroinflammation
neuroprotection
neurodegeneration
Online-Zugang:https://www.mdpi.com/2218-273X/15/11/1629
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