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Microglia-Mediated Phagocytosis in Alzheimer’s Disease: Mechanisms, Heterogeneity, and Therapeutic Insights

Microglia are the resident immune cells of the CNS, maintaining brain homeostasis partially through phagocytosis. In Alzheimer’s disease (AD), microglial phagocytosis is significantly impaired, contributing to the accumulation of pathological aggregates. Microglial phenotypes are dynamic and can shi...

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Auteurs principaux: Halimatu Hassan, Charlotte Rawlinson, Yu-Long Lan, Stuart Jenkins, Ruoli Chen
Format: Artigo
Langue:Inglês
Publié: MDPI AG 2025-11-01
Collection:Biomolecules
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Accès en ligne:https://www.mdpi.com/2218-273X/15/11/1629
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