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Lipid membrane remodeling by myristic acid treatment reverses Parkinson’s disease α-synuclein phenotypes in patient neurons

Abstract Despite the lipid-rich nature of the brain, defining the role of lipid metabolism in neurodegenerative disease and targeting lipid metabolic pathways for disease modification are in their infancy. In Parkinson’s disease, Lewy body dementia, and other synucleinopathies, disease-associated fo...

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Бібліографічні деталі
Автори: Julian Avila Pacheco, Gleidia Sauli, Luis Fonseca-Ornelas, Haley Cirka, Deepa Kumari, Morgan Hazo, Sarah Jeanfavre, Pedro H. Vendramini, Christina R. Muratore, Clary B. Clish, Dennis Selkoe, Saranna Fanning
Формат: Artigo
Мова:Inglês
Опубліковано: Nature Portfolio 2026-04-01
Серія:npj Metabolic Health and Disease
Онлайн доступ:https://doi.org/10.1038/s44324-026-00110-8
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