Lipid membrane remodeling by myristic acid treatment reverses Parkinson’s disease α-synuclein phenotypes in patient neurons

Abstract Despite the lipid-rich nature of the brain, defining the role of lipid metabolism in neurodegenerative disease and targeting lipid metabolic pathways for disease modification are in their infancy. In Parkinson’s disease, Lewy body dementia, and other synucleinopathies, disease-associated fo...

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Detalhes bibliográficos

Principais autores:	Julian Avila Pacheco, Gleidia Sauli, Luis Fonseca-Ornelas, Haley Cirka, Deepa Kumari, Morgan Hazo, Sarah Jeanfavre, Pedro H. Vendramini, Christina R. Muratore, Clary B. Clish, Dennis Selkoe, Saranna Fanning
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2026-04-01
Colecção:	npj Metabolic Health and Disease
Acesso em linha:	https://doi.org/10.1038/s44324-026-00110-8
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