High glucose treatment promotes extracellular matrix proteome remodeling in Müller glial cells

Background The underlying pathomechanisms in diabetic retinopathy (DR) remain incompletely understood. The aim of this study was to add to the current knowledge about the particular role of retinal Müller glial cells (RMG) in the initial processes of DR. Methods Applying a quantitative proteomic wor...

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Hlavní autoři:	Sandra Sagmeister, Juliane Merl-Pham, Agnese Petrera, Cornelia A. Deeg, Stefanie M. Hauck
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	PeerJ Inc. 2021-05-01
Edice:	PeerJ
Témata:	Diabetic retinopathy Secreted phosphoprotein 1 (SPP1) Osteopontin Neurodegeneration Organotypic explant cultures Translational large animal model
On-line přístup:	https://peerj.com/articles/11316.pdf
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