Proteomic Phenotyping of Stimulated Müller Cells Uncovers Profound Pro-Inflammatory Signaling and Antigen-Presenting Capacity

Müller cells are the main macroglial cells of the retina exerting a wealth of functions to maintain retinal homoeostasis. Upon pathological changes in the retina, they become gliotic with both protective and detrimental consequences. Accumulating data also provide evidence for a pivotal role of Müll...

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Bibliographic Details

Main Authors:	Adrian Schmalen, Lea Lorenz, Antje Grosche, Diana Pauly, Cornelia A. Deeg, Stefanie M. Hauck
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2021-10-01
Series:	Frontiers in Pharmacology
Subjects:	Müller cells atypical antigen-presenting cell immune response diabetic retinopathy oxidative phosphorylation complement system
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2021.771571/full
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