Th17-like cells and immunosuppressive macrophages infiltrate tertiary lymphoid structures with distinct maturation status in soft-tissue sarcoma

Abstract Tertiary lymphoid structures (TLSs) have been associated with favorable clinical outcome and improved responses to immune checkpoint inhibitors in soft-tissue sarcomas (STSs). However, due to their rarity and high heterogeneity, information regarding the mechanisms involved in TLS formation...

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Hlavní autoři:	Giulia Petroni, Federico Scolari, Guido Scoccianti, Annarita Palomba, Daniela Greto, Simone Romagnoli, Ilaria Palchetti, Andrea Bernini, Enrico Caliman, Simone Polvani, Filippo Nozzoli, Beatrice Menicacci, Giulia Nannini, Domenico Andrea Campanacci, Serena Pillozzi, Lorenzo Antonuzzo
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Publishing Group 2025-12-01
Edice:	Cell Death and Disease
On-line přístup:	https://doi.org/10.1038/s41419-025-08376-4
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!