Th17-like cells and immunosuppressive macrophages infiltrate tertiary lymphoid structures with distinct maturation status in soft-tissue sarcoma

Abstract Tertiary lymphoid structures (TLSs) have been associated with favorable clinical outcome and improved responses to immune checkpoint inhibitors in soft-tissue sarcomas (STSs). However, due to their rarity and high heterogeneity, information regarding the mechanisms involved in TLS formation...

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Detalhes bibliográficos

Principais autores:	Giulia Petroni, Federico Scolari, Guido Scoccianti, Annarita Palomba, Daniela Greto, Simone Romagnoli, Ilaria Palchetti, Andrea Bernini, Enrico Caliman, Simone Polvani, Filippo Nozzoli, Beatrice Menicacci, Giulia Nannini, Domenico Andrea Campanacci, Serena Pillozzi, Lorenzo Antonuzzo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2025-12-01
coleção:	Cell Death and Disease
Acesso em linha:	https://doi.org/10.1038/s41419-025-08376-4
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