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Mechanism of the age-related decrease of epinephrine-stimulated lipolysis in isolated rat adipocytes: beta-adrenergic receptor binding, adenylate cyclase activity, and cyclic AMP accumulation.

beta-adrenergic binding ([3H]dihydroalprenolol), adenylate cyclase activity, and cAMP accumulation were measured in adipocytes to investigate whether the mechanism of decreased hormone-sensitive lipolytic response with age was mediated through membrane-associated events. The dose of epinephrine requ...

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Detalles Bibliográficos
Principais autores: E M Dax, J S Partilla, R I Gregerman
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 1981-08-01
Series:Journal of Lipid Research
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S0022227520373314
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