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Location of the axon initial segment assembly can be predicted from neuronal shape

Summary: The axon initial segment (AIS) is located at the proximal axon demarcating the boundary between axonal and somatodendritic compartments. The AIS facilitates the generation of action potentials and maintenance of neuronal polarity. In this study, we show that the location of AIS assembly, as...

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Hauptverfasser: Zhuang Xu, Christopher N. Angstmann, Yuhuang Wu, Holly Stefen, Esmeralda Parić, Thomas Fath, Paul M.G. Curmi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2024-03-01
Schriftenreihe:iScience
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Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2589004224004851
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