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Spectrin condensates provide a nidus for assembling the axonal membrane-associated periodic skeleton

Summary: In axons, α/β-spectrins, adducin, and actin filaments assemble into a lattice underneath the plasma membrane, but the mechanistic events leading to this membrane-associated periodic skeleton (MPS) are unclear. Visualizing MPS-components in developing axons, we found distal focal patches con...

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Principais autores: Nicholas P. Boyer, Rohan Sharma, Theresa Wiesner, Christopher Parperis, Antoine Delamare, Florence Pelletier, Nicolas Jullien, Anshul M. Bhatt, Leonardo A. Parra-Rivas, Patrick J. Kearney, Farbod Shavarebi, Christophe Leterrier, Subhojit Roy
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2026-01-01
Serier:iScience
Fag:
Neuroscience
Molecular neuroscience
Cell biology
Online adgang:http://www.sciencedirect.com/science/article/pii/S2589004225027154
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